The Case Comprehensive Cancer Center
A partnership organization supporting all cancer-related research efforts at Case Western Reserve University, University Hospitals Case Medical Center, and the Cleveland Clinic.
Hosted by the Case Comprehensive Cancer Center in partnership with Karmanos Cancer Institute, The Ohio State University Comprehensive Cancer Center, Roswell Park Cancer Institute, University of Michigan Comprehensive Cancer Center, and University of Pittsburgh Cancer Institute
A Comprehensive Cancer Center Designated by the National Cancer Institute
One of 41 nationwide.
The only one in Northeast Ohio.
Accepting Applications for a Start Date of September 1, 2013
Candidates with an MD, PhD, or MD/PhD degree, strong quantitative skills, and an interest in a career in genetics research are encouraged to apply.
School of Medicine Researchers Discover New Target for Personalized Cancer Therapy
A common cancer pathway causing tumor growth is being targeted by a number of new cancer drugs and shows promising results. A team of researchers at Case Western Reserve University School of Medicine has developed a novel method to disrupt this growth-signaling pathway, with findings that suggest a new treatment for breast, colon, melanoma and other cancers.
The research team has pinpointed the cancer abnormality to a mutation in a gene called PIK3CA that results in a mutant protein, which may be an early cancer switch. By disrupting the mutated signaling pathway, the Case Western Reserve team, led by John Wang, associate professor in the Department of Genetics and Case Comprehensive Cancer Center, inhibited the growth of cancer cells, opening the possibility to new cancer therapies. [more]
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